Simultaneously recording local luminance responses, spatial and temporal interactions in the visual system with m-sequences

In this paper, an extended multifocal VEP/ERG paradigm, referred to as the unified multifocal electroretinography and visual evoked potential paradigm (UMEV), is presented. This paradigm allows a simultaneous recording of luminance responses, temporal interactions, spatial interactions and spatial-temporal interactions. Two studies were conducted to demonstrate the capability and validity of the UMEV. The results show that the UMEV system derives a significant spatial interaction VEP in addition to a similar luminance response (mfERG) and pattern reversal VEP (mfVEP) to the VERIS system. Second, the amplitude of spatial interaction VEP is diminished by increasing the distance between two stimuli while the amplitude of temporal interaction VEP remain relatively unchanged.